At age 15, she moved to Mexico City to participate in the reality show Pop Stars, where she was a finalist and member of the band, t'detila and recording an album with the same name. She dated Alexis Ayala from 2006 to 2009.
In 2003 she joined the Center for Arts Education Televisa to study acting. In 2005 Ana Brenda did the casting for the telenovela Barrera de amor, produced by Ernesto Alonso staying with one of the roles youth playing "Juanita".
In 2006, came the cast of Grease on the production work of Julissa, the same year she made a cameo on the soap Duelo de Pasiones, produced by Juan Osorio, in the role of "Claudia".
After the departure of the vedette Niurka "Los 5 Magníficos" program was called for production to lead the red team, as also removed a week later.
In 2008 stars in the film "Divina Confusion", directed by Salvador Garcini. That same year she received a job offer from the producer MaPat for the protagonist of the telenovela Juro Que Te Amo, produced by MaPat playing "Violeta Madrigal", the soap opera began in July 2008 and ended in February 2009.
In 2009 the producer Carla Estrada offered her the antagonistic role in the telenovela Sortilegio; in this telenovela, she was given the role of "Maura Albarran" who is someone who is in love with "Alejandro Lombardo" who was played by William Levy (actor).
Also in 2009, Ana Brenda was offered the role in participating in the Mexican hit series Mujeres Asesinas, where she showed her fans the type of character she is capable in becoming. In this episode she worked with other extremly good actresses such as Paty Navidad and as well as Galilea Montijo. In this same year she was offered to as well participate in another hit series Tiempo Final
In 2010 she gives life to "Aurora" in the remake of Teresa, where she played the best friend of the protagonist who is Angelique Boyer. In addition to participating in the musical Timbiriche el Musical where she played "Carol".
La que no podia amar (2011-2012) - Ana Paola
Teresa (2010–2011) - Aurora Coronel Alcazar de Sanchez
Sortilegio (2009) - Maura Albarrán
Juro Que Te Amo (2008–2009) - Violeta Madrigal Campero
Duelo de Pasiones (2006) - Claudia
Barrera de amor (2005–2006) - Juana "Juanita" Sánchez